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EFNA2 (Ephrin A2) Antibody (YA8256)(PBS only)

(Synonyms: ELF-1; EPLG6; HEK7-L; LERK-6; LERK6)

EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • EFNA2 (Ephrin A2) Antibody (YA8256)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 21.3 kDa
Immunogen

Full length human recombinant protein of human EFNA2 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    EFNA2 cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis

  • Subcellular Localization

    Cell membrane

  • Isoforms & Post-Translational Modification

    O43921: 213 amino acids, molecular weight 23878 Da.

  • Subunit

    Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5

  • SwissProt ID

    O43921

  • Synonyms

    ELF-1; EPLG6; HEK7-L; LERK-6; LERK6

EFNA2 (Ephrin A2) Antibody (YA8256)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • EFNA2 (Ephrin A2) Antibody (YA8256)(PBS only) Product Image
    1/16
  • EFNA2 (Ephrin A2) Antibody (YA8256)(PBS only) Product Image