GLO1 Antibody (YA413)
(Synonyms: Aldoketomutase; glo1; GLOD1; Glx I; GLYI)GLO1 Antibody (YA413) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GLO1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:100 |
Product Details
GLO1 Antibody (YA413) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GLO1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 21 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 21 kDa
Entrez Gene: 2739 Human ; 109801 Mouse ; 294320 Rat
SwissProt: Q04760 Human ; Q9CPU0 Mouse ; Q6P7Q4 Rat
OMIM: 138750 Human
Synthetic peptide corresponding to Human GLO1 aa10-50.
Endogenous
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294). Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (PubMed:19199007). Required for normal osteoclastogenesis (By similarity)
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Isoforms & Post-Translational Modification
Q04760 has 2 isomers: Q04760-1: 20778 Da (predicted); Q04760-2: 19043 Da (predicted).
Glutathionylation at Cys-139 inhibits enzyme activity;Phosphorylated at Thr-107 in the presence of CaMK2. However, this is a consensus site for phosphorylation by CK2 so phosphorylation may be mediated by CK2 rather than CaMK2. Phosphorylation is induced by TNF and suppresses the TNF-induced transcriptional activity of NF-kappa-B;Exists in a nitric oxide (NO)-modified form. The exact nature of the modification is unknown, but it suppresses the TNF-induced transcriptional activity of NF-kappa-B -
Subunit
Homodimer
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SwissProt ID
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Synonyms
Aldoketomutase; glo1; GLOD1; Glx I; GLYI
Documentation
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