IL-13 Receptor alpha 1 Antibody (YA4138)(PBS only)
(Synonyms: IL13RA1; NR4; CT19; IL-13Ra)IL-13 Receptor alpha 1 Antibody (YA4138) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-13 Receptor alpha 1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
IL-13 Receptor alpha 1 Antibody (YA4138) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-13 Receptor alpha 1.
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Host Mouse
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 49 kDa
Purified recombinant fragment of human CD213A1 (AA: extra 22-343) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
IL-13 Receptor alpha 1 binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is widely distributed. The highest concentrations are found in the heart, liver, skeletal muscle, and ovaries; the lowest concentrations are found in the brain, lungs, and kidneys. It is also present in B cells, T cells, and endothelial cells. -
Isoforms & Post-Translational Modification
P78552 has 2 isomers: P78552-1: 48760 Da (predicted); P78552-2: 31659 Da (predicted).
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Subunit
Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1. Interacts with IL4 (PubMed:18243101)
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SwissProt ID
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Synonyms
IL13RA1; NR4; CT19; IL-13Ra
Documentation
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