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Max Dimerization Protein 3 Antibody (YA2229)

(Synonyms: bHLHc13; mxd3; Myx)
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Max Dimerization Protein 3 Antibody (YA2229) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Max Dimerization Protein 3.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • Max Dimerization Protein 3 Antibody (YA2229) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
Dilution Ratio 1:1000-1:2000 1:100-1:200 1:50-1:100

Product Details

Description

Max Dimerization Protein 3 Antibody (YA2229) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Max Dimerization Protein 3.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 28 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 23 kDa
Species Reactivity Database
Immunogen

A synthesized peptide derived from human MAD3 aa100-162/206.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Max Dimerization Protein 3 transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    Q9BW11 has 4 isomers: Q9BW11-1: 23477 Da (predicted); Q9BW11-2: 22384 Da (predicted); Q9BW11-3: 22065 Da (predicted); Q9BW11-4: 42821 Da (predicted).

  • Subunit

    Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.

  • SwissProt ID

    Q9BW11

  • Gene ID
    83463 [NCBI]
  • Synonyms

    bHLHc13; mxd3; Myx

  • Research Field

    Epigenetics and Nuclear Signaling

Max Dimerization Protein 3 Antibody (YA2229) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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