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  5. NUDC Antibody (YA2371)

NUDC Antibody (YA2371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUDC.

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20 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Obtenir un devis  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Description

  • Références

Description

NUDC Antibody (YA2371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NUDC.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Masse moléculaire
Predicted band size: 38 kDa;
Observed band size: 42 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human NUDC aa280-331/331.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
IP
IP: Immunoprecipitation
1:50
FC
FC: Flow Cytometry
1:50-1:100
Sensitivity Endogenous Pureté Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Livraison

Shipping with blue ice.
Background
Function：Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (PubMed:12679384, PubMed:12852857, PubMed:25789526). Necessary for cytokinesis and cell proliferation (PubMed:12679384, PubMed:12852857)
Subcellular Localization：Cytoplasm, cytoskeleton; Nucleus; Cytoplasm, cytoskeleton, spindle; Midbody
Expression：
Tissue_specificity:Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in human pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart

Induction:Up-regulated in actively dividing hematopoietic precursor cells. Up-regulated in cultured erythroleukemia TF-1 cells by granulocyte-macrophage colony-stimulating factor. Strongly down-regulated during maturation of erythroid precursor cells
Subunit：Interacts with PAFAH1B1 (By similarity). Interacts with PLK1 (PubMed:12852857). Part of a complex containing PLK1, NUDC, dynein and dynactin (PubMed:12852857). Interacts with DCDC1 (PubMed:22159412). Interacts with EML4 (via WD repeats) (PubMed:25789526)
Database

Entrez Gene: 10726 Human ; 18221 Mouse ; 29648 Rat

SwissProt: Q9Y266 Human ; O35685 Mouse ; Q63525 Rat

OMIM: 610325 Human

Research Field

-
Synonyms
HNUDC; MNUDC; NPD011; nudC; SIG92
Documentation
User Guide for Antibodies (1077 KB)
Références

NUDC Antibody (YA2371) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
NUDC Antibody (YA2371)
Cat. No.:
HY-P82626
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