POLDIP2 Antibody (YA1680)(PBS only)
(Synonyms: p38; POLD4; PDIP38)POLDIP2 Antibody (YA1680) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POLDIP2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20 |
Product Details
POLDIP2 Antibody (YA1680) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POLDIP2.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 38 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 42 kDa
A synthetic peptide of human POLDIP2
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
POLDIP2 is involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1)[1][2].
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Subcellular Localization
Mitochondrion matrix; Nucleus
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Subunit
Interacts with PCNA and POLD2 (PubMed:12522211). Interacts with SSBP1 (PubMed:16428295). Interacts with PRIMPOL; leading to enhance DNA polymerase activity of PRIMPOL (PubMed:26984527). Interacts with POLH (PubMed:20554254). Interacts with POLD1; leading to stimulate DNA polymerase activity of POLD1 (PubMed:24191025)
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SwissProt ID
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Synonyms
p38; POLD4; PDIP38
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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