PSMD2 (Proteasome 26S S2) Antibody (YA7816)

Cat. No.: HY-P88132: Data Sheet COA
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PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Documentation

Description

PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 100 kDa

Species Reactivity

Human, Dog, Rat, Monkey, Mouse

SwissProt ID

Q13200

Immunogen

Full length human recombinant protein of human PSMD2 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from 293T (lane2(20μg), Jurkat (lane3(20μg), Hela (lane4(20μg) and NIH/3T3 (lane5(20μg) using PSMD2 (Proteasome 26S S2) Antibody (HY-P88132). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80993, 1/10,000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (HY-P8004 ,1/10,000) was used for 1 hour at room temperature.

Background

Function：Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair|Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1

Expression：
Tissue_Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta

Isoforms & Post-Translational Modification：Q13200 has three isomers: Q13200-1: 100200 Da (predicted); Q13200-2: 82193 Da (predicted); Q13200-3: 85606 Da (predicted).

Subunit：Component of the 19S proteasome regulatory particle complex

Synonyms

P97; RPN1; S2; TRAP2

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)