RHOG Antibody (YA6744)

Cat. No.: HY-P87051: Data Sheet User Guide for Antibodies
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RHOG Antibody (YA6744) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RHOG.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

RHOG Antibody (YA6744) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RHOG.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 21 kDa;

Observed band size: 21 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Monkey

SwissProt ID

P84095

Gene ID

391 [NCBI]

Immunogen

Synthetic peptide within human RHOG aa 1-50 / 191.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
FC FC: Flow Cytometry	1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays a role in immunological synaptic F-actin density and architecture organization (PubMed:33513601). Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity (PubMed:33513601). Required for the formation of membrane ruffles during macropinocytosis (PubMed:15133129). Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes (PubMed:17875742). Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM) (PubMed:33513601). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells (PubMed:33513601). Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D (PubMed:33513601). Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells (PubMed:33513601)|(Microbial infection) In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry

Subcellular Localization：Cell membrane

Isoforms & Post-Translational Modification：P84095: 191 amino acids, molecular weight 21309 Da.

Subunit：Interacts with ARHGEF26 (PubMed:15133129)

Synonyms

ARHG antibody; Ras homolog family member G antibody; Rho G antibody; Rho related GTP binding protein RhoG precursor antibody; Rho-related GTP-binding protein RhoG antibody; RHOG antibody; RHOG_HUMAN antibody;

Documentation

User Guide for Antibodies (1077 KB)