Stim2 Antibody
(Synonyms: KIAA1482, STIM2, Stromal interaction molecule 2)Stim2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Stim2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
Stim2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Stim2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 110 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 68; 83; 93 kDa
Purified recombinant protein of human Stim2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Stim2 plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx
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Subcellular Localization
Endoplasmic reticulum membrane
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Expression
Tissue_Specificity: Expressed in all tissues and tumor cell lines examined. -
Isoforms & Post-Translational Modification
Stim2 has 3 isoforms, Q9P246-1: amino acid length is 746, molecular weight is 83971 Da (predicted); Q9P246-2: amino acid length is 841, molecular weight is 93957 Da (predicted); Q9P246-3: amino acid length is 599, molecular weight is 68026 Da (predicted).可发生糖基化Stim2 存在 3 个异构体，Q9P246-1：氨基酸个数为 746 个，分子量为 83971 Da (预测)；Q9P246-2：氨基酸个数为 841 个，分子量为 93957 Da (预测)；Q9P246-3：氨基酸个数为 599 个，分子量为 68026 Da (预测)。Glycosylated
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Subunit
Oligomer with STIM1.
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SwissProt ID
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Synonyms
KIAA1482, STIM2, Stromal interaction molecule 2
Documentation
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