TCTP Antibody (YA038)
(Synonyms: Translationally-controlled tumor protein; TCTP; Fortilin; Histamine-releasing factor; HRF; p23)Based on 1 Customer Validation
TCTP Antibody (YA038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCTP.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF, FC
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:200-1:500 | 1:100-1:1000 |
Product Details
TCTP Antibody (YA038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCTP.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 20 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 20 kDa
Entrez Gene: 7178 Human ; 22070 Mouse ; 116646 Rat
SwissProt: P13693 Human ; P63028 Mouse ; P63029 Rat
OMIM: 600763 Human
Synthetic peptide corresponding to Human TCTP.The exact sequence is proprietary to MCE.
Endogenous
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Involved in calcium binding and microtubule stabilization (PubMed:12167714, PubMed:15162379, PubMed:15958728). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (PubMed:18325344)
-
Subcellular Localization
Cytoplasm
-
Expression
Tissue_specificity:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC) . Expressed in placenta and prostate
Induction:Down-regulated in response to enterovirus 71 (EV71) infection -
Isoforms & Post-Translational Modification
P13693 has 2 isomers: P13693-1: 19595 Da (predicted); P13693-2: 15597 Da (predicted).
-
Subunit
Homodimer (By similarity). Interacts with STEAP3 (PubMed:15319436). Interacts with TSC22D1; interaction results in the destabilization of TSC22D1 protein (PubMed:18325344)
-
SwissProt ID
-
Synonyms
Translationally-controlled tumor protein; TCTP; Fortilin; Histamine-releasing factor; HRF; p23
Documentation