THAP11 Antibody (YA4426)(PBS only)
(Synonyms: RONIN; CTG-B43a; CTG-B45d; HRIHFB2206; THAP11)THAP11 Antibody (YA4426) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to THAP11.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, IHC-P, ICC/IF, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
THAP11 Antibody (YA4426) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to THAP11.
-
Host Mouse
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 44 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 34 kDa
Purified recombinant fragment of human THAP11 aa 137-313.
affinity purified.
Non-conjugated
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
THAP11 transcription factor, which has both transcriptional activation and repression activities. Also modulates chromatin accessibility. In complex with HCFC1 and ZNF143, regulates the expression of several genes, including AP2S1, ESCO2, OPHN1, RBL1, UBXN8 and ZNF32. May regulate the expression of genes that encode both cytoplasmic and mitochondrial ribosomal proteins. Required for normal mitochondrial development and function. Regulates mitochondrial gene expression, including that of components of the electron transport chain. Involved in the maintainance of pluripotency in early embryonic cells, possibly through its action on mitochondrial maturation which is required to meet high energy demands of these cells. Required for early development of retina, preventing premature exit of retinal progenitor cells from the cell cycle. This effect may also be mediated by its action on mitochondria. Through the regulation of MMACHC gene expression, controls cobalamin metabolism. Required for normal brain development and neural precursor differentiation. Involved in cell growth[1][2][3][4].
-
Subcellular Localization
Nucleus; Cytoplasm
-
Expression
Tissue_specificity:Expression in skin fibroblasts -
Subunit
Forms homodimers (PubMed:31905202). Interacts via HBM with HCFC1 (PubMed:31905202). Forms a complex with HCFC1 and ZNF143 (Probable)
-
SwissProt ID
-
Synonyms
RONIN; CTG-B43a; CTG-B45d; HRIHFB2206; THAP11
Documentation
Powered by Bioz
