Vitamin D Binding Protein Antibody (YA009)(PBS only)

Cat. No.: HY-P80930A: Data Sheet User Guide for Antibodies
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Vitamin D Binding Protein Antibody (YA009) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitamin D Binding Protein.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Vitamin D Binding Protein Antibody (YA009) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitamin D Binding Protein.

Host

Rabbit

분자량

Predicted band size: 53 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P02774

Gene ID

2638 [NCBI]

Immunogen

Synthetic peptide corresponding to Human Vitamin D Binding protein aa255-265.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	affinity purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation

Subcellular Localization：Secreted

Expression：
Tissue_specificity:Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine

Isoforms & Post-Translational Modification：P02774 has 3 isomers: P02774-1: 52918 Da (predicted); P02774-2: 39496 Da (predicted); P02774-3: 55077 Da (predicted).
Allele GC*1S is O-glycosylated at Thr-436 (PubMed:20079467). The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated (PubMed:17360250). The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated

Subunit：Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

Research Field

Signal Transduction

Synonyms

GC; Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component

각종 서류

User Guide for Antibodies (1077 KB)