Vitamin D Binding Protein Antibody (YA009)(PBS only)

製品番号: HY-P80930A: データシート User Guide for Antibodies
FAQs
Technical Support

Vitamin D Binding Protein Antibody (YA009) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitamin D Binding Protein.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Vitamin D Binding Protein Antibody (YA009) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitamin D Binding Protein.

Host

Rabbit

分子量

Predicted band size: 53 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P02774

Gene ID

2638 [NCBI]

Immunogen

Synthetic peptide corresponding to Human Vitamin D Binding protein aa255-265.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

純度	affinity purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation

Subcellular Localization：Secreted

Expression：
Tissue_specificity:Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine

Isoforms & Post-Translational Modification：P02774 has 3 isomers: P02774-1: 52918 Da (predicted); P02774-2: 39496 Da (predicted); P02774-3: 55077 Da (predicted).
Allele GC*1S is O-glycosylated at Thr-436 (PubMed:20079467). The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated (PubMed:17360250). The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated

Subunit：Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

Research Field

Signal Transduction

Synonyms

GC; Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component

ドキュメンテーション

User Guide for Antibodies (1077 KB)

Vitamin D Binding Protein Antibody (YA009)(PBS only) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Vitamin D Binding Protein Antibody (YA009)(PBS only)

Product Detail

Background

説明

Vitamin D Binding Protein Antibody (YA009)(PBS only) 関連分類

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