Anticancer agent 220
Anticancer agent 220 is a chromanone derivative with anticancer effects. Anticancer agent 220 shows highly potent activity in the colon cancer cell lines. Anticancer agent 220 induces apoptosis and cell cycle arrest in cells.
For research use only. We do not sell to patients.
- Formula: C22H19Cl3N2O6
- Molecular Weight:513.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Anticancer agent 220 (compound 14C) displays cytotoxicity in HCT-116 cells with an IC50 of 53.3 µg/mL. Anticancer agent 220 induces DNA fragmentation in HCT-116 cells, down-regulate the expression level of CDK4 as well as the anti-apoptotic gene Bcl-2 and up-regulate the expression of the pro-apoptotic genes P53 and Bax[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 513.76
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Formula C22H19Cl3N2O6
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SMILES
COC(C1=C(OC(C)=CC1=O)C=C2OCC(OCC)=O)=C2/C=N/NC3=C(Cl)C=C(Cl)C=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 220 Related Classifications
HY-158407 Related Classifications
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