Cntn6 - contactin 6 Gene

Also Known as NB-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53870

Summary

Predicted to enable cell-cell adhesion mediator activity. Acts upstream of or within positive regulation of Notch signaling pathway. Located in parallel fiber to Purkinje cell synapse and plasma membrane. Is anchored component of presynaptic membrane. Is expressed in brain; spinal cord; and tooth. Orthologous to human CNTN6 (contactin 6). [provided by Alliance of Genome Resources, Apr 2022]

Cntn6 Products (15)

mRNA Protein Name
NM_001411154.1 NP_001398083.1 contactin-6 isoform a precursor
NM_001411155.1 NP_001398084.1 contactin-6 isoform a precursor
NM_001411156.1 NP_001398085.1 contactin-6 isoform a precursor
NM_001411157.1 NP_001398086.1 contactin-6 isoform a precursor
NM_001411158.1 NP_001398087.1 contactin-6 isoform a precursor
NM_001411159.1 NP_001398088.1 contactin-6 isoform a precursor
NM_001411160.1 NP_001398089.1 contactin-6 isoform a precursor
NM_001411161.1 NP_001398090.1 contactin-6 isoform a precursor
NM_001411162.1 NP_001398091.1 contactin-6 isoform b precursor
NM_001411163.1 NP_001398092.1 contactin-6 isoform b precursor
NM_001411164.1 NP_001398093.1 contactin-6 isoform c precursor
NM_001411165.1 NP_001398094.1 contactin-6 isoform c precursor
NM_001411166.1 NP_001398095.1 contactin-6 isoform c precursor
NM_001411167.1 NP_001398096.1 contactin-6 isoform c precursor
NM_017383.4 NP_059079.2 contactin-6 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
18046458 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within positive regulation of Notch signaling pathway IEP
IEP: Inferred from expression pattern
25074942 MGI
Cellular Component GO Annotation Evidence Verweise Source
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
19672956 MGI
is active in parallel fiber to Purkinje cell synapse IEP
IEP: Inferred from expression pattern
19672956 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
25074942 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
19672956 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
19672956 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
19672956 MGI
is active in presynaptic membrane IEP
IEP: Inferred from expression pattern
19672956 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

contactin-6

  • mNB-3

  • neural recognition molecule NB-3

Cntn6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Cntn6 Q9JMB8 Chl1 Mus musculus P70232
IF
18046458
Intra
Cntn6 Q9JMB8 Chl1 Mus musculus P70232
Anti Bait CoIP
18046458
Intra
Cntn6 Q9JMB8 Chl1 Mus musculus P70232
Anti Tag CoIP
18046458
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02931 CNTN6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20385 Cntn6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26895 Cntn6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntn6 NCBI NCBI:27255