CNTN6 - contactin 6 Gene

Also Known as NB3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27255

About CNTN6

Cytogenetic location: 3p26.3 Genomic coordinates (GRCh38): 3:1,093,024-1,404,217 (from NCBI)

This gene has 6 transcripts (splice variants), 123 orthologues and 36 paralogues. Biased expression in thyroid (RPKM 3.8), lung (RPKM 1.4) and 3 other tissues.

Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

CNTN6 Products (16)

mRNA Protein Name
NM_001289080.2 NP_001276009.1 contactin-6 isoform 1 precursor
NM_001289081.2 NP_001276010.1 contactin-6 isoform 2
NM_001349350.2 NP_001336279.1 contactin-6 isoform 1 precursor
NM_001349351.2 NP_001336280.1 contactin-6 isoform 1 precursor
NM_001349352.2 NP_001336281.1 contactin-6 isoform 1 precursor
NM_001349353.2 NP_001336282.1 contactin-6 isoform 1 precursor
NM_001349354.2 NP_001336283.1 contactin-6 isoform 1 precursor
NM_001349355.2 NP_001336284.1 contactin-6 isoform 1 precursor
NM_001349356.2 NP_001336285.1 contactin-6 isoform 3 precursor
NM_001349357.2 NP_001336286.1 contactin-6 isoform 4 precursor
NM_001349358.2 NP_001336287.1 contactin-6 isoform 5 precursor
NM_001349359.2 NP_001336288.1 contactin-6 isoform 6
NM_001349360.2 NP_001336289.1 contactin-6 isoform 6
NM_001349361.2 NP_001336290.1 contactin-6 isoform 6
NM_001349362.2 NP_001336291.1 contactin-6 isoform 6
NM_014461.4 NP_055276.1 contactin-6 isoform 1 precursor

CNTN6 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (28 - 108)

I-set

I-set: Immunoglobulin I-set domain (125 - 204)

I-set

I-set: Immunoglobulin I-set domain (233 - 309)

I-set

I-set: Immunoglobulin I-set domain (318 - 403)

I-set

I-set: Immunoglobulin I-set domain (410 - 496)

I-set

I-set: Immunoglobulin I-set domain (501 - 592)

fn3

fn3: Fibronectin type III domain (600 - 687)

fn3

fn3: Fibronectin type III domain (805 - 891)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1028 a.a.
Protein Preferred Names Protein Names

contactin-6

  • neural adhesion molecule

Recombinant CNTN6 Proteins

Cat. No. Product Name Accession Purity
HY-P76278 CNTN6/Contactin-6 Protein, Human (HEK293, Fc) Q9UQ52/NP_055276.1 (D20-S999) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Chromosome 3pter-P25 Deletion Syndrome

  • 3p- Syndrome

  • 3p Deletion Syndrome

  • Distal Monosomy 3p

  • Chromosome 3, Monosomy 3p

  • 3p Partial Monosomy Syndrome

  • Chromosome 3, Deletion 3p

  • Chromosome 3p Deletion Syndrome

  • Del Syndrome

  • Deletion 3p

  • Monosomy 3p

  • Partial Monosomy 3p

  • Distal 3p Deletion

  • Monosomy 3pter

  • Telomeric Monosomy 3p

  • Chromosome Deletion Syndrome 3pter-P25
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Coffin-Siris Syndrome 6

  • CSS6

  • Coffin-Siris Syndrome, Type 6
Transient Tic Disorder
Retinitis Pigmentosa 35

  • RP35

  • Retinitis Pigmentosa-35

  • Retinitis Pigmentosa, Type 35
Cerebellar Ataxia Type 9

  • Sca9
Atrial Septal Defect 6

  • ASD6

  • Atrial Heart Septal Defect 6

  • Septal Defect, Atrial, Type 6
Autism Spectrum Disorder

  • Asd

  • Autism Spectrum Disorders

  • Autistic Continuum

  • Pervasive Developmental Disorder

  • Pervasive Development Disorder

  • Autistic Behavior

  • Autistic Disorder

  • Autistic

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Childhood Autism

  • Kanner Syndrome

  • Pervasive Developmental Delay Nos

  • Pervasive Developmental Disorder, Not Otherwise Specified
Gilles De La Tourette Syndrome

  • Tourette Syndrome

  • Tourette Disorder

  • GTS

  • Ts

  • Gilles De La Tourette'S Syndrome

  • Motor-Verbal Tic Disorder

  • Guinon'S Disease

  • Psychogenic Tics

  • Tourette'S Syndrome

  • Chronic Motor And Vocal Tic Disorder

  • Td

  • Tourette'S Disease

  • Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]

  • Combined Vocal And Multiple Motor Tic Disorder

  • Tic De La Tourette
Attention Deficit-Hyperactivity Disorder

  • Attention Deficit Hyperactivity Disorder

  • ADHD

  • Attention Deficit Disorder

  • Attention Deficit-Hyperactivity Disorder, Susceptibility To

  • Attention Deficit Disorder With Hyperactivity

  • Hyperkinetic Disorder

  • Hyperactivity Of Childhood

  • Attention-Deficit/Hyperactivity Disorder

  • Add

  • Addh

  • Attention Deficit

  • Attention Deficit Disorder Of Childhood With Hyperactivity

  • Attention Deficit Disorder With Hyperactivity Syndrome

  • Hyperkinetic Syndrome

  • Attention-Deficit Hyperactivity Disorder

  • Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

  • Disturbance Of Activity And Attention

  • Disorder Of Activity And Attention

  • Adhd - [Attention Deficit Hyperactivity Disorder]

  • Hyperkinetic Disorders

  • Disorder Of Activity And Attention With Hyperkinesia

  • Attention Deficit Syndrome With Hyperactivity
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02931 CNTN6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20385 Cntn6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26895 Cntn6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CNTN6 VGNC VGNC:27539
Canis familiaris CNTN6 VGNC VGNC:39437
Mus musculus CNTN6 MGD MGI:1858223
Felis catus CNTN6 VGNC VGNC:78409
Rattus norvegicus CNTN6 RGD RGD:62008
Macaca mulatta CNTN6 VGNC VGNC:84197
Others CNTN6 NCBI