STYK1 - serine/threonine/tyrosine kinase 1 Gene

Also Known as NOK; SuRTK106

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55359

About STYK1

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,618,923-10,674,052 (from NCBI)

This gene has 6 transcripts (splice variants), 219 orthologues and 32 paralogues. Biased expression in colon (RPKM 5.3), stomach (RPKM 4.5) and 13 other tissues.

Summary

Receptor Protein Tyrosine Kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]

STYK1 Products (1)

mRNA	Protein	Name
NM_018423.3	NP_060893.2	tyrosine-protein kinase STYK1

STYK1 Protein Structure

Pkinase_Tyr

0
100
200
300
400
422 a.a.

Protein Preferred Names	Protein Names
tyrosine-protein kinase STYK1	novel oncogene with kinase domain

STYK1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	STYK1	Q6J9G0	HSP90AB1	Homo sapiens	P08238	Pull Down	32707033
Intra	STYK1	Q6J9G0	HSP90AB1	Homo sapiens	P08238	Affinity Chrom	35384245
Intra	STYK1	Q6J9G0	GSK3B	Homo sapiens	P49841	Anti Tag CoIP	23010592

Cross: Cross-species interaction Intra: Intraspecies interaction

STYK1 Antibodies

Art. -Nr.	Produktname	Anwendung	Reactivity
HY-P85300	STYK1/NOK Antibody (YA4992)	IHC-P, ELISA	Human
HY-P85300A	STYK1/NOK Antibody (YA4992)(PBS only)	IHC-P, ELISA	Human

Related Diseases

Diseases	Alias
Developmental And Epileptic Encephalopathy 34	DEE34 Epileptic Encephalopathy, Early Infantile, 34 Eiee34 Developmental And Epileptic Encephalopathy, 34 Early Infantile Epileptic Encephalopathy 34
Branchiootorenal Syndrome 1	Melnick-Fraser Syndrome BOR1 Branchiootorenal Dysplasia Branchiootorenal Syndrome 1, With Or Without Cataracts Bor Syndrome 1 Branchiootorenal Dysplasia 1 Branchio-Oto-Renal Dysplasia 1 Branchio-Oto-Renal Syndrome Type 1 Branchiootorenal Syndrome, With/Without Cataract, Type 1 Branchio-Oto-Renal Syndrome
Cataract 11, Multiple Types	Cataract, Posterior Polar, 4 Ctpp4 Cpp4 Cataract 11 Multiple Types CTRCT11 Cataract 11, Syndromic, Autosomal Recessive Cataract 11 With Microphthalmia And Neurodevelopmental Abnormalities Posterior Polar Cataract 4 Posterior Polar Cataract, 4 Cataract Posterior Polar 4 Syndromic Cataract 11 Cataract, Type 11, Multiple Types
Cervix Carcinoma	Cancer Of Cervix Carcinoma Of Cervix Carcinoma Cervix Uteri Carcinoma Of The Cervix Uteri
Tinea Capitis	Dermatophytosis Of Scalp Scalp Ringworm Dermatophytosis Of Scalp Or Beard Tinea Capitis Due To Trichophyton Rubrum Trichophyton Rubrum Tinea Capitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS13996	STYK1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21772	Styk1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28289	Styk1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	STYK1	VGNC	VGNC:65823
Bos taurus	STYK1	VGNC	VGNC:35451
Rattus norvegicus	STYK1	RGD	RGD:1564211
Mus musculus	STYK1	MGD	MGI:2141396
Macaca mulatta	STYK1	VGNC	VGNC:78165
Others	STYK1	NCBI