N3-C4-NHS ester
Based on 1 Customer Validation
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.53%
- CAS. Nr.: 478801-48-8
- Formel: C9H12N4O4
- Molecular Weight:240.22
-
Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
-
HY-126521
N3-C3-NHS esterADC Linker -
HY-126523
N3-C5-NHS esterADC Linker -
HY-126520
N3-C2-NHS esterADC Linker -
HY-W588704
4-Azidobutyric acidPROTAC Linker -
HY-W123015
6-Azidohexanoic acidDrug Intermediate -
HY-130143
Biotin-PEG3-azidePROTAC Linker -
HY-130544
5-Azidopentanoic acidCrosslinker -
HY-151655
11-Azidoundecanoic acidLpIA Substrate
Alle ADC Linkers Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
|
Non-cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 478801-48-8
-
Appearance Solid-Liquid Mixture
-
Molecular Weight 240.22
-
Formel C9H12N4O4
-
Color Colorless to light yellow
-
SMILES
O=C(ON1C(CCC1=O)=O)CCCCN=[N+]=[N-]
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
-
Data Sheet (266 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
N3-C4-NHS ester Related Classifications
HY-126522 Related Classifications
Powered by Bioz