Pipazethate hydrochloride
Based on 4 publication(s) in Google Scholar
Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant .
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- CAS. Nr.: 6056-11-7
- Formel: C21H26ClN3O3S
- Molecular Weight:435.97
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Pipazethate hydrochloride
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 6056-11-7
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Molecular Weight 435.97
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Formel C21H26ClN3O3S
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SMILES
O=C(N1C2=CC=CC=C2SC3=C1N=CC=C3)OCCOCCN4CCCCC4.Cl
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Synonyms
SKF 70230A hydrochloride; SQ 15874 hydrochloride; Pipazetate hydrochloride
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
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Environ Int
PPARγ-SMAD6 axis-mediated inhibition of osteogenic differentiation is involved in BPS-induced osteoporosis. [Abstract]2025 Apr:198:109442. PMID: 40215917 -
Radiother Oncol
Modulation of the local angiotensin II: Augmentation of ferroptosis and radiosensitivity in nasopharyngeal carcinoma via the HIF-1α-HILPDA axis. [Abstract]2025 Feb:203:110686. PMID: 39709027 -
J Pharmacol Sci
EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome. [Abstract]2021 Jul;146(3):121-124. PMID: 34030794 -
Neurosci Lett
A novel angiotensin II type 2 receptor antagonist TDI05 alleviates the peripheral neuropathic pain. [Abstract]2025 Aug 28:138369. PMID: 40885515
Reinheit & Dokumentation
Verweise
[1]. Squires RF, et al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441(1-2):15-22. doi: 10.1016/0006-8993(88)91378-9. [Content Brief]
[2]. Vakil BJ, et al. Trial of pipazethate as an antitussive. Clin Pharmacol Ther. 1966 Jul-Aug;7(4):515-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Pipazethate hydrochloride Related Classifications
HY-W742300 Related Classifications
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