2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Pipazethate

Pipazethate  (Synonyms: SKF 70230A; SQ 15874; Pipazetate)

Cat. No.: HY-B2090 Purity: 99.0%
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Handling Instructions Technical Support

Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant.

For research use only. We do not sell to patients.

Pipazethate

Pipazethate Chemical Structure

CAS No. : 2167-85-3

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1 mg In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Pipazethate:

Pipazethate Related Antibodies

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Description

Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].

Molecular Weight

399.51

Formula

C21H25N3O3S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N1C2=NC=CC=C2SC3=CC=CC=C13)OCCOCCN4CCCCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

1 M HCl : 100 mg/mL (250.31 mM; Need ultrasonic)

H2O : 1 mg/mL (2.50 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5031 mL 12.5153 mL 25.0307 mL
5 mM 0.5006 mL 2.5031 mL 5.0061 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / 1 M HCl 1 mM 2.5031 mL 12.5153 mL 25.0307 mL 62.5767 mL
1 M HCl 5 mM 0.5006 mL 2.5031 mL 5.0061 mL 12.5153 mL
10 mM 0.2503 mL 1.2515 mL 2.5031 mL 6.2577 mL
15 mM 0.1669 mL 0.8344 mL 1.6687 mL 4.1718 mL
20 mM 0.1252 mL 0.6258 mL 1.2515 mL 3.1288 mL
25 mM 0.1001 mL 0.5006 mL 1.0012 mL 2.5031 mL
30 mM 0.0834 mL 0.4172 mL 0.8344 mL 2.0859 mL
40 mM 0.0626 mL 0.3129 mL 0.6258 mL 1.5644 mL
50 mM 0.0501 mL 0.2503 mL 0.5006 mL 1.2515 mL
60 mM 0.0417 mL 0.2086 mL 0.4172 mL 1.0429 mL
80 mM 0.0313 mL 0.1564 mL 0.3129 mL 0.7822 mL
100 mM 0.0250 mL 0.1252 mL 0.2503 mL 0.6258 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Pipazethate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pipazethate2167-85-3SKF 70230A SQ 15874 PipazetateSQ15874SQ 15874SQ-15874GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid Receptorpyridobenzothiazine derivativeantitussivecough supressantInhibitorinhibitorinhibit

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