NP603
NP603 is a potent inhibitor of FGF receptor 1, exhibiting remarkable activity against endothelial proliferation in HUVEC cells stimulated by rhFGF-2, with a minimum effective dose of 0.4 microM.
For research use only. We do not sell to patients.
- CAS No.: 949164-80-1
- Formula: C26H26N2O5
- Molecular Weight:446.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
18.2 μM
Compound: NP603
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Inhibition of rhFGF2-induced cellular proliferation of HUVEC
Inhibition of rhFGF2-induced cellular proliferation of HUVEC
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[PMID: 17618113] |
| HUVEC | IC50 |
18.2 μM
Compound: NP603
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Inhibition of rhFGF2-induced HUVEC proliferation
Inhibition of rhFGF2-induced HUVEC proliferation
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[PMID: 19110422] |
Chemical Information
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CAS No. 949164-80-1
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Molecular Weight 446.50
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Formula C26H26N2O5
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SMILES
O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC(C4=CC(OC)=CC(OC)=C4)=C3)=O)=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NP603 Related Classifications
HY-112353 Related Classifications
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