Human TP53 mRNA
Human TP53 mRNA encodes the human tumor protein p53 (TP53) protein, a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. TP53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Gene ID
Gene Information
TP53 - tumor protein p53
Also Known as
P53; BCC7; LFS1; BMFS5; TRP53
Chemical Information
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Sequence
MEEPQSDPSV EPPLSQETFS DLWKLLPENN VLSPLPSQAM DDLMLSPDDI EQWFTEDPGP DEAPRMPEAA PPVAPAPAAP TPAAPAPAPS WPLSSSVPSQ KTYQGSYGFR LGFLHSGTAK SVTCTYSPAL NKMFCQLAKT CPVQLWVDST PPPGTRVRAM AIYKQSQHMT EVVRRCPHHE RCSDSDGLAP PQHLIRVEGN LRVEYLDDRN TFRHSVVVPY EPPEVGSDCT TIHYNYMCNS SCMGGMNRRP ILTIITLEDS SGNLLGRNSF EVRVCACPGR DRRTEEENLR KKGEPHHELP PGSTKRALPN NTSSSPQPKK KPLDGEYFTL QIRGRERFEM FRELNEALEL KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
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Species
Human
Purity & Documentation
Hot Topics
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Topics
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Most Recent
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Topics Cellular Senescence & Age-related Diseases
Cellular senescence is a stable state of cell-cycle arrest triggered by diverse forms of cellular stress, including telomere shortening, DNA damage, oncogene activation, mitochondrial dysfunction, oxidative stress, and chromatin perturbation.
2026-06-18
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Topics Senolytics and Senomorphic Strategies in Aging Research
Cellular senescence is a stable state of cell-cycle arrest triggered by DNA damage, telomere attrition, oncogenic signaling, and other forms of cellular stress.
2026-06-18
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Topics Molecular Spark of cGAS-STING-Mediated Cellular Senescence
Cellular senescence is a stress-response program characterized by irreversible cell-cycle arrest and the senescence-associated secretory phenotype (SASP), originally recognized as a tumor-suppressive mechanism and now considered a central process in aging biology, inflammation, and cancer research.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)