B-Raf IN 8
B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM.
For research use only. We do not sell to patients.
- CAS No.: 1215313-19-1
- Formula: C18H17N3O2
- Molecular Weight:307.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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B-Raf 70.65 ± 0. nM (IC50) |
Chemical Information
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CAS No. 1215313-19-1
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Molecular Weight 307.35
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Formula C18H17N3O2
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SMILES
O=C1CCC(C2=CC=C(/N=C/C3=CC=C(OC)C=C3)C=C2)=NN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B-Raf IN 8 Related Classifications
HY-147853 Related Classifications
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