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  4. Bathocuproine disulfonate disodium

Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.

For research use only. We do not sell to patients.

CAS No. : 52698-84-7

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Based on 2 publication(s) in Google Scholar

Other Forms of Bathocuproine disulfonate disodium:

Bathocuproine disulfonate disodium Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Bathocuproine disulfonate disodium

Cell Proliferation/Viability Assay

    Bathocuproine disulfonate disodium purchased from MedChemExpress. Usage Cited in: Fitoterapia. 2025 Apr 23:106567.  [Abstract]

    Ferroptosis inhibitor could reverse the proliferation suppression of DLN on MDA-MB-231 cells. The cell viability assays of MDA-MB-231 cells treated with DLN and that combination with indicated survival pathway inhibitors for 72 h, including apoptosis inhibitor Z-VAD-FMK (10 μM), necroptosis inhibitor Necro-1 (2 μM), autophagy inhibitor Chloroquine (2 μM), pyroptosis inhibitor VX 765 (50 μM), cuproptosis inhibitor Bathocuproine disulfonate disodium (10 μM) or ferroptosis inhibitor Fer-1 (10 μM).

    • Biological Activity

    • Purity & Documentation

    • Customer Review

    Description

    Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.

    In Vitro

    Disodium bathocuproine disulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Bathocuproine disulfonate disodium Related Antibodies
    Molecular Weight

    564.54

    Formula

    C26H18N2Na2O6S2
    CAS No.
    Appearance

    Solid

    Color

    Off-white to light brown

    SMILES

    CC1=NC2=C(N=C3C)C(C(C4=CC=CC=C4)=C3)=CC=C2C(C5=CC=CC=C5)=C1.O=S(C)(O[Na])=O.O=S(C)(O[Na])=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, protect from light, stored under nitrogen

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (88.57 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.7714 mL 8.8568 mL 17.7135 mL
    5 mM 0.3543 mL 1.7714 mL 3.5427 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.53%

    SDS (393 KB)

    COA (246 KB) HNMR (283 KB) LCMS (94 KB)

    Handling Instructions (2659 KB)

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 1.7714 mL 8.8568 mL 17.7135 mL 44.2838 mL
    5 mM 0.3543 mL 1.7714 mL 3.5427 mL 8.8568 mL
    10 mM 0.1771 mL 0.8857 mL 1.7714 mL 4.4284 mL
    15 mM 0.1181 mL 0.5905 mL 1.1809 mL 2.9523 mL
    20 mM 0.0886 mL 0.4428 mL 0.8857 mL 2.2142 mL
    25 mM 0.0709 mL 0.3543 mL 0.7085 mL 1.7714 mL
    30 mM 0.0590 mL 0.2952 mL 0.5905 mL 1.4761 mL
    40 mM 0.0443 mL 0.2214 mL 0.4428 mL 1.1071 mL
    50 mM 0.0354 mL 0.1771 mL 0.3543 mL 0.8857 mL
    60 mM 0.0295 mL 0.1476 mL 0.2952 mL 0.7381 mL
    80 mM 0.0221 mL 0.1107 mL 0.2214 mL 0.5535 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Bathocuproine disulfonate disodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Bathocuproine disulfonate disodium52698-84-7Biochemical Assay Reagentsbiochemical assayreagentInhibitorinhibitorinhibit

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