BAY 11-7085 (Standard)
BAY 11-7085 (Standard) is the analytical standard of BAY 11-7085 (HY-10257). This product is intended for research and analytical applications. BAY 11-7085 (BAY 11-7083) is an inhibitor of NF-κB activation and phosphorylation of IκBα; it stabilizes IκBα with an IC50 of 10 μM.
For research use only. We do not sell to patients.
- CAS No.: 196309-76-9
- Formula: C13H15NO2S
- Molecular Weight:249.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 196309-76-9
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Molecular Weight 249.33
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Formula C13H15NO2S
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SMILES
N#C/C=C/S(C(C=C1)=CC=C1C(C)(C)C)(=O)=O
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Synonyms
BAY 11-7083 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pierce JW, et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesionmolecule expression show anti-inflammatory effects in vivo. J Biol Chem. 1997 Aug 22;272(34):21096-103. [Content Brief]
[2]. Nasu K, et al. Application of the nuclear factor-kappaB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E16-23. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)