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Besufetamig

(Synonyms: ONO-4685)
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Based on 1 Customer Validation

Besufetamig is a bispecific antibody targeting programmed cell death 1 (PD-1) and CD3ε chain. Besufetamig modulates the activity of immune cells, exerting immunosuppressive and antineoplastic activities. Besufetamig is promising for research of cancers.

For research use only. We do not sell to patients.

  • Purity: 99.98%
  • CAS No.: 3037124-22-1
  • Molecular Weight:146.01 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Besufetamig
  • Experimental Validation Results for Besufetamig
  • Experimental Validation Results for Besufetamig
  • Experimental Validation Results for Besufetamig
  • Experimental Validation Results for Besufetamig
  • Besufetamig Chemical Structure
    Besufetamig Chemical Structure
CAS No.: 3037124-22-1
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Besufetamig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) can bind Besufetamig. The EC50 for this effect is 5.266 ng/mL.

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Besufetamig. The EC50 for this effect is 41.78 ng/mL.

  • 1/16

    Flow Cytometry analysis of Hela cells labelling PD-1 (red) with Besufetamig (anti-PD-1) (HY-P991122, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow Cytometry analysis of Jurkat cells labelling CD3E (red) with Besufetamig (anti-CD3E) (HY-P991122, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Besufetamig Chemical Structure
    1/16
  • Besufetamig
  • Immobilized PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) can bind Besufetamig. The EC50 for this effect is 5.266 ng/mL.
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Besufetamig. The EC50 for this effect is 41.78 ng/mL.
  • Flow Cytometry analysis of Hela cells labelling PD-1 (red) with Besufetamig (anti-PD-1) (HY-P991122, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow Cytometry analysis of Jurkat cells labelling CD3E (red) with Besufetamig (anti-CD3E) (HY-P991122, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa