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Bevantolol hydrochloride (Standard)

(Synonyms: SOM3355 (Standard))

Bevantolol hydrochloride (Standard) (SOM3355 (Standard)) is the analytical standard of Bevantolol hydrochloride (HY-121186). This product is intended for research and analytical applications. Bevantolol hydrochloride (SOM3355) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol hydrochloride blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol hydrochloride reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol hydrochloride is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease.

For research use only. We do not sell to patients.

  • CAS No.: 42864-78-8
  • Formula: C20H28ClNO4
  • Molecular Weight:381.89
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Bevantolol hydrochloride (Standard) Chemical Structure
    Bevantolol hydrochloride (Standard) Chemical Structure
CAS No.: 42864-78-8
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  • Bevantolol hydrochloride (Standard) Chemical Structure
    Bevantolol hydrochloride (Standard) Chemical Structure
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  • Bevantolol hydrochloride (Standard)