2. GPCR/G Protein
  3. Leukotriene Receptor
  4. BLT2 antagonist-1

BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease.

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BLT2 antagonist-1 Chemical Structure

BLT2 antagonist-1 Chemical Structure

CAS No. : 2069220-61-5

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BLT2 antagonist-1 Related Antibodies

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Description

BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].

IC50 & Target

BLT2

224 nM (IC50)

Molecular Weight

435.49

Formula

C26H26FNO4
CAS No.
SMILES

O=C(CCCC)N(C1=CC=CC(F)=C1)CC2=CC=C(C3=CC=C(OCC(O)=O)C=C3)C=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BLT2 antagonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BLT2 antagonist-12069220-61-5Leukotriene ReceptorBLT2 antagonistinflammatory airway diseasesInhibitorinhibitorinhibit

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