Bromo-PEG8-Boc
Based on 1 Customer Validation
Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 1623792-00-6
- Formel: C23H45BrO10
- Molecular Weight:561.50
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1623792-00-6
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Appearance Liquid (Density: 1.18 g/cm3)
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Molecular Weight 561.50
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Formel C23H45BrO10
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCBr
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 87.5 mg/mL (155.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7809 mL | 8.9047 mL | 17.8094 mL | 44.5236 mL |
| 5 mM | 0.3562 mL | 1.7809 mL | 3.5619 mL | 8.9047 mL | |
| 10 mM | 0.1781 mL | 0.8905 mL | 1.7809 mL | 4.4524 mL | |
| 15 mM | 0.1187 mL | 0.5936 mL | 1.1873 mL | 2.9682 mL | |
| 20 mM | 0.0890 mL | 0.4452 mL | 0.8905 mL | 2.2262 mL | |
| 25 mM | 0.0712 mL | 0.3562 mL | 0.7124 mL | 1.7809 mL | |
| 30 mM | 0.0594 mL | 0.2968 mL | 0.5936 mL | 1.4841 mL | |
| 40 mM | 0.0445 mL | 0.2226 mL | 0.4452 mL | 1.1131 mL | |
| 50 mM | 0.0356 mL | 0.1781 mL | 0.3562 mL | 0.8905 mL | |
| 60 mM | 0.0297 mL | 0.1484 mL | 0.2968 mL | 0.7421 mL | |
| 80 mM | 0.0223 mL | 0.1113 mL | 0.2226 mL | 0.5565 mL | |
| 100 mM | 0.0178 mL | 0.0890 mL | 0.1781 mL | 0.4452 mL |
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