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  5. Bruceanic acid D

Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia.

For research use only. We do not sell to patients.

Bruceanic acid D

Bruceanic acid D Chemical Structure

CAS No. : 132587-61-2

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Bruceanic acid D Related Antibodies

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Description

Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia[1].

In Vitro

Bruceanic acid D (compound 5) exhibits cytotoxic activity against P-388 murine leukemia cells with an ED50 of 0.77 μg/mL, and does not show cytotoxicity against A-549 or HCT-8 cells at the tested threshold[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bruceanic acid D Related Antibodies
Molecular Weight

568.57

Formula

C27H36O13
CAS No.
SMILES

COC([C@]12[C@@]3([H])[C@@]4(CO2)[C@]([C@H]([C@@H]1O)O)([H])[C@](C)([C@@H](C[C@@]4([H])OC([C@@H]3OC(/C=C(C)/C(C)(O)C)=O)=O)C(C)=O)CC(O)=O)=O
Structure Classification
Initial Source

Brucea antidysenterica
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Bruceanic acid D Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bruceanic acid D132587-61-2OthersP-388 lymphocytic leukemia cellsBrucea antidysentericaHCT-8 cellshuman colon carcinoma cellshuman lung carcinoma cellsP-388 murine leukemia cellsA-549 cellsInhibitorinhibitorinhibit

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