Bruceanic acid D
Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia.
For research use only. We do not sell to patients.
- CAS No.: 132587-61-2
- Formula: C27H36O13
- Molecular Weight:568.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Bruceanic acid D (compound 5) exhibits cytotoxic activity against P-388 murine leukemia cells with an ED50 of 0.77 μg/mL, and does not show cytotoxicity against A-549 or HCT-8 cells at the tested threshold[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 132587-61-2
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Molecular Weight 568.57
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Formula C27H36O13
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SMILES
COC([C@]12[C@@]3([H])[C@@]4(CO2)[C@]([C@H]([C@@H]1O)O)([H])[C@](C)([C@@H](C[C@@]4([H])OC([C@@H]3OC(/C=C(C)/C(C)(O)C)=O)=O)C(C)=O)CC(O)=O)=O
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Structure Classification
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Initial Source
Brucea antidysenterica
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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