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Cat. No.: HY-187012

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BRAF ligand-2

BRAF ligand-2 is a BRAF ligand that can be used to synthesize PROTACs, such as Tagarafdeg (HY-153341).

For research use only. We do not sell to patients.

CAS No.: 2882167-76-0
Formula: C₂₆H₂₉FN₆O₅S
Molecular Weight:556.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BRAF ligand-2 Chemical Structure

CAS No.: 2882167-76-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BRAF ligand-2 is a BRAF ligand that can be used to synthesize PROTACs, such as Tagarafdeg (HY-153341)^[1].

IC₅₀ & Target^[1]

Braf

All Raf Isoforms :

Chemical Information

CAS No. 2882167-76-0
Molecular Weight 556.61
Formula C₂₆H₂₉FN₆O₅S
SMILES

O=C(C1=C2)N(C=NC1=CC=C2OC(C(F)=CC=C3N[S](N(C)CC)(=O)=O)=C3C#N)[C@@H]4CC5(OC4)CCNCC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sowa M E, et al. Preclinical evaluation of CFT1946 as a selective degrader of mutant BRAF for the treatment of BRAF driven cancers[J]. Cancer Research, 2022, 82(12_Supplement): 2158-2158.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BRAF ligand-2

All Raf Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BRAF ligand-2 Related Classifications

HY-187012 Related Classifications