CTBS - chitobiase Gene

Also Known as CTB

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1486

About CTBS

Cytogenetic location: 1p22.3 Genomic coordinates (GRCh38): 1:84,549,611-84,574,440 (from NCBI)

This gene has 4 transcripts (splice variants), 203 orthologues and 6 paralogues. Ubiquitous expression in prostate (RPKM 12.0), liver (RPKM 10.6) and 25 other tissues.

Summary

Chitobiase is a lysosomal Glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010]

CTBS Products (1)

mRNA Protein Name
NM_004388.3 NP_004379.1 di-N-acetylchitobiase precursor

CTBS Protein Structure

Glyco_hydro_18

Glyco_hydro_18: Glycosyl hydrolases family 18 (108 - 357)

  • 0
  • 100
  • 200
  • 300
  • 385 a.a.
Protein Preferred Names Protein Names

di-N-acetylchitobiase

  • chitobiase, di-N-acetyl-

Related Diseases

Diseases Alias
Mannosidosis, Beta A, Lysosomal

  • Beta-Mannosidosis

  • Lysosomal Beta-Mannosidase Deficiency

  • Beta-Mannosidase Deficiency

  • Beta-D-Mannosidosis

  • Mannosidosis, Beta

  • MANSB

  • Lysosomal Beta A Mannosidosis
Mannosidosis, Alpha B, Lysosomal

  • Alpha-Mannosidosis

  • Lysosomal Alpha-D-Mannosidase Deficiency

  • Deficiency Of Alpha-Mannosidase

  • Alpha-Mannosidase B Deficiency

  • Mannosidosis

  • MANSA

  • Mannosidosis, Alpha-, Types I And Ii

  • Alpha-D-Mannosidosis

  • Alpha-Mannosidase Deficiency

  • Α-Mannosidosis

  • Alpha Mannosidase B Deficiency

  • Mannosidosis, Alpha B Lysosomal

  • Lysosomal Alpha B Mannosidosis

  • Alpha-Mannosidosis, Infantile Form

  • Lysosomal Alpha-D-Mannosidase Deficiency, Infantile Form

  • Alpha-Mannosidosis, Adult Form

  • Lysosomal Alpha-D-Mannosidase Deficiency, Adult Form

  • Alpha-Mannosidosis Types I And Ii

  • Mannosidase Deficiency Diseases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-134964 CTB 99.93% Phase 4
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99727 Mazorelvimab Inhibitor 97% Phase 3

Pre-clinical Phase

Bioactive Molecules (18)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P3394 Cholera toxin B subunit, from vibrio cholerae 95.00% Unkown
HY-181824 Cholera toxin-IN-1 Inhibitor / Unkown
HY-D2254 CTB probe-1 / Unkown
HY-P3394A Cholera toxin B subunit-AF350 / Unkown
HY-P3394B Cholera toxin B subunit-AF405 / Unkown
HY-P3394C Cholera toxin B subunit-AF488 / Unkown
HY-P3394D Cholera toxin B subunit-AF568 / Unkown
HY-P3394E Cholera toxin B subunit-AF594 / Unkown
HY-P3394H Cholera toxin B subunit-AF647 / Unkown
HY-P3394I Cholera toxin B subunit-AF680 / Unkown
HY-P3394J Cholera toxin B subunit-Cy3 / Unkown
HY-P3394K Cholera toxin B subunit-Cy5 / Unkown
HY-P3394L Cholera toxin B subunit-Cy7 / Unkown
HY-P3394M Cholera toxin B subunit-Biotin / Unkown
HY-P3394N Cholera toxin B subunit-Rhodamine / Unkown
HY-P3394O Cholera toxin B subunit-HRP / Unkown
HY-P3394P Cholera toxin B subunit-Fluorescein / Unkown
HY-RS03285 CTBS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99513 Zamerovimab 99.54% Unkown
HY-P992340 CTB006 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CTBS VGNC VGNC:71540
Mus musculus CTBS MGD MGI:1921495
Felis catus CTBS VGNC VGNC:107519
Canis familiaris CTBS VGNC VGNC:39688
Bos taurus CTBS VGNC VGNC:27786
Rattus norvegicus CTBS RGD RGD:621338
Others CTBS NCBI