HERPUD2 - HERPUD family member 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64224

About HERPUD2

This gene has 7 transcripts (splice variants), 264 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 12.4), ovary (RPKM 12.2) and 25 other tissues.

Summary

Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to act upstream of or within spermatogenesis. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

HERPUD2 Products (1)

mRNA Protein Name
NM_022373.5 NP_071768.3 homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HERPUD2 Protein Structure

ubiquitin

ubiquitin: Ubiquitin family (20 - 88)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
Protein Preferred Names Protein Names

homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

  • homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 2

HERPUD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HERPUD2 Q9BSE4 TAS2R10 Homo sapiens Q9NYW0
Validated Y2H
32296183
Intra
HERPUD2 Q9BSE4 SLC39A9 Homo sapiens Q9NUM3
Validated Y2H
32296183
Intra
HERPUD2 Q9BSE4 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra
HERPUD2 Q9BSE4 IER3IP1 Homo sapiens Q9Y5U9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06133 HERPUD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HERPUD2 MGD MGI:1915393
Canis familiaris HERPUD2 VGNC VGNC:41664
Rattus norvegicus HERPUD2 RGD RGD:1307343
Felis catus HERPUD2 VGNC VGNC:102607
Bos taurus HERPUD2 VGNC VGNC:29817
Macaca mulatta HERPUD2 VGNC VGNC:73216
Others HERPUD2 NCBI