TAS2R10 - taste 2 receptor member 10 Gene

Also Known as TRB2; T2R10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50839

About TAS2R10

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,825,219-10,826,358 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 199 orthologues and 23 paralogues.

Summary

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the Taste Receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the Taste Receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

TAS2R10 Products (1)

mRNA Protein Name
NM_023921.2 NP_076410.1 taste receptor type 2 member 10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables bitter taste receptor activity IDA
IDA: Inferred from direct assay
20022913 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: Inferred from direct assay
20022913 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TAS2R10 Protein Structure

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 296)

  • 0
  • 100
  • 200
  • 307 a.a.
Protein Preferred Names Protein Names

taste receptor type 2 member 10

  • taste receptor, family B, member 2

TAS2R10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TAS2R10 Q9NYW0 RTP4 Homo sapiens Q96DX8
Y2H Prey Pooling
32296183
Intra
TAS2R10 Q9NYW0 RTP4 Homo sapiens Q96DX8
Y2H Array
32296183
Intra
TAS2R10 Q9NYW0 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra
TAS2R10 Q9NYW0 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra
TAS2R10 Q9NYW0 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
TAS2R10 Q9NYW0 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
TAS2R10 Q9NYW0 HERPUD2 Homo sapiens Q9BSE4
Y2H Array
32296183
Intra
TAS2R10 Q9NYW0 HERPUD2 Homo sapiens Q9BSE4
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14216 TAS2R10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TAS2R10 RGD RGD:2314260
Canis familiaris TAS2R10 VGNC VGNC:47115
Others TAS2R10 NCBI