Nagilactone C
Based on 1 Customer Validation
Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 24338-53-2
- Formula: C19H22O7
- Molecular Weight:362.37
-
Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| AGS | IC50 |
2.3 μM
Compound: 7j
|
Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| HeLa | IC50 |
3.3 μM
Compound: 7j
|
Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| HepG2 | IC50 |
14 μM
Compound: 7j
|
Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| MDA-MB-231 | IC50 |
5 μM
Compound: 7j
|
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| P388 | IC50 |
0.33 μg/mL
Compound: 1
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 1800635] |
| PANC-1 | IC50 |
>40 μM
Compound: 7j
|
Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
Chemical Information
-
CAS No. 24338-53-2
-
Appearance Solid
-
Molecular Weight 362.37
-
Formula C19H22O7
-
Color White to off-white
-
SMILES
C[C@@]1(C2=C3)[C@]4([H])[C@]([C@@H](O)[C@@H]5[C@H]1O5)(C(O[C@]4([H])[C@H](O)C2=C(C(C)C)OC3=O)=O)C
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nagilactone C Related Classifications
HY-N3215 Related Classifications
Powered by Bioz