Siponimod (Standard)
Siponimod (BAF-312) (Standard) is the analytical standard of Siponimod. This product is intended for research and analytical applications. Siponimod is an orally active, blood-brain barrier penetrant dual agonist of S1P1/S1P5, with EC50 values of 0.39 nM and 0.98 nM, respectively. Siponimod induces S1P1 internalization, activates GIRK channels, inhibits lymphocyte egress, reduces peripheral lymphocyte counts, triggers transient bradycardia, prevents synaptic neurodegeneration, promotes remyelination, alleviates demyelination, and prevents the loss of GABAergic interneurons. Siponimod can be used in research related to multiple sclerosis.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 1230487-00-9
- Formula: C29H35F3N2O3
- Molecular Weight:516.60
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-12355
SiponimodS1P1/S1P5 Agonist -
HY-10569
PonesimodS1P1 Agonist -
HY-12288
OzanimodS1P Receptor Modulator -
HY-15425
PF-543SPHK1 Inhibitor -
HY-12005
Fingolimod hydrochlorideS1P Receptors Modulator -
HY-13822
SKI IISphK/DES1 Inhibitor -
HY-19736
TY-52156LPL Receptor Antagonist -
HY-108496
Sphingosine-1-phosphateS1PR Agonist -
HY-12789
EtrasimodS1P1 Receptor Antagonist -
HY-11063
FingolimodS1P Antagonist -
HY-10968
CYM5442S1P1 Receptor Agonist -
HY-W008947
SEW2871S1P1 Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 1230487-00-9
-
Molecular Weight 516.60
-
Formula C29H35F3N2O3
-
SMILES
O=C(C1CN(CC2=CC=C(/C(C)=N/OCC3=CC=C(C4CCCCC4)C(C(F)(F)F)=C3)C=C2CC)C1)O
-
Synonyms
BAF-312 (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Hot Topics
-
All
-
Topics
-
Most Recent
-
Oldest
-
Topics Synaptic Plasticity & Brain Health
Synaptic plasticity is the activity-, experience-, development-, and injury-dependent modification of synaptic strength, number, and structure, and it remains a central mechanism for learning, memory, sensory adaptation, and brain health.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Siponimod (Standard) Related Classifications
HY-12355R Related Classifications
Powered by Bioz