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Cat. No.: HY-149818

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8BTC

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM.

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CAS No.: 3064070-24-9
Formule: C₁₀H₉Cl₂NO
Masse moléculaire:230.09

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

8BTC Chemical Structure

CAS No.: 3064070-24-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM^[1].

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Chemical Information

CAS No. 3064070-24-9
Masse moléculaire 230.09
Formule C₁₀H₉Cl₂NO
SMILES

CC(N1CCC2=C1C=CC(Cl)=C2Cl)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Benjamin N Atkinson, et al. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur J Med Chem. 2023 May 5;251:115132. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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8BTC

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