AZ11657312
AZ11657312 is a P2X7 receptor antagonist with activity to restore stress natriuresis. AZ11657312 significantly increased renal medullary perfusion, only in mice treated with angiotensin II. AZ11657312 improves tissue oxygenation by blocking P2X7R, especially in areas of the kidney that are underoxygenated. Administration of AZ11657312 increased sodium excretion up to sixfold while normalizing blood pressure.
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- CAS No.: 804561-22-6
- Formule: C26H35N3O3
- Masse moléculaire:437.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 804561-22-6
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Masse moléculaire 437.57
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Formule C26H35N3O3
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SMILES
O=C(CC12CC3CC(CC(C2)C3)C1)NC4=CC(C(N5CC6OC(C5)CNC6)=O)=CC=C4C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AZ11657312 Related Classifications
HY-122282 Related Classifications
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