BMS-229724
BMS-229724 is an orally active and tight-binding cytosolic phospholipase A2 (cPLA2) inhibitor with an IC50 of 2.8 μM. BMS-229724 can inhibit the production of arachidonic acid and eicosanoids in U937 cells, neutrophils, platelets, and other cells. BMS-229724 has anti-inflammatory activity and can be used in the research of diseases such as skin inflammation.
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- CAS No.: 221914-85-8
- Formule: C27H25Cl2F3O5S
- Masse moléculaire:589.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
cPLA2 |
Chemical Information
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CAS No. 221914-85-8
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Masse moléculaire 589.45
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Formule C27H25Cl2F3O5S
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SMILES
O=C(CCC1=CC=C(OCCS(=O)(CCOC(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)=O)C=C1)C(F)(F)F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)