1613402-20-2
1613402-20-2
Chemical Structure
PAO-Nap
- CAS No.: 1613402-20-2
- Formula:C24H24AsN3O5
- Molecular Weight:509.39
IUPAC Name: (4-(6-(6-amino-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)hexanamido)phenyl)arsonous acid
InChIKey: CVWSXPBPPSJPCI-UHFFFAOYSA-N
SMILES: O[As](C1=CC=C(NC(CCCCCN(C(C2=CC=C(N)C3=CC=CC4=C23)=O)C4=O)=O)C=C1)O
Biological Activity:
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].
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PAO-Nap | PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase. |
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References
Keywords
