CCG 258001
CCG 258001 is a GRK inhibitor with IC50 values of 0.29, 51.8, and 33 µM against GRK2, GRK1, and GRK5, respectively. CCG 258001 inhibits GRK activity in cardiomyocytes and other muscle cells. CCG 258001 is applicable to the research of heart diseases, including heart failure, myocardial hypertrophy, and hypertension.
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- CAS No.: 2055990-96-8
- Formule: C20H22FN3O
- Masse moléculaire:339.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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GRK2 0.29 μM (IC50) |
GRK5 33 μM (IC50) |
CCG 258001 (5 min) potently inhibits GRK2 with an IC50 of 0.29 µM, while it shows weak inhibitory effects on GRK1 and GRK5[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055990-96-8
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Masse moléculaire 339.41
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Formule C20H22FN3O
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SMILES
C(OC=1C=C2C(=CC1)NN=C2)[C@H]3[C@@H](CCN(C)C3)C4=CC=C(F)C=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CCG 258001 Related Classifications
HY-120168 Related Classifications
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