DAD dichloride
DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C26H42Cl2N6O
- Masse moléculaire:525.56
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
DAD is not permanently charged, and the uncharged form enables the photoswitch to rapidly and effectively cross biological barriers and thereby access and photosensitize retinal neurons. DAD selectively photosensitizes retinal neurons upstream of retinal ganglion cells (RGCs). DAD is capable of restoring retinal ganglion cell light responses to blue or white light[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
Masse moléculaire 525.56
-
Formule C26H42Cl2N6O
-
SMILES
O=C(C[NH+](CC)CC)NC(C=C1)=CC=C1/N=N/C2=CC=C(N(CC)CC[NH+](CC)CC)C=C2.[Cl-].[Cl-]
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)