Deoxylimonin
Based on 1 Customer Validation
Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.51%
- CAS No.: 989-23-1
- Formule: C26H30O7
- Masse moléculaire:454.51
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Natural Product Library
HY-L021
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Anti-Cancer Compound Library
HY-L025
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Terpenoids Library
HY-L056
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Orally Active Compound Library
HY-L061
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Anti-Breast Cancer Compound Library
HY-L074
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Microbial Metabolite Library
HY-L084
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HY-L107
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HY-L115
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Natural Product Diversity Scaffold Library
HY-L245
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
5.5 μM
Compound: 11d
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Antiproliferative activity against human MCF7 cells incubated for 48 hrs by [3H]-thymidine incorporation assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by [3H]-thymidine incorporation assay
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[PMID: 33289552] |
| MDA-MB-435 | IC50 |
1.7 μM
Compound: 11d
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Antiproliferative activity against human MDA-MB-435 cells incubated for 48 hrs by [3H]-thymidine incorporation assay
Antiproliferative activity against human MDA-MB-435 cells incubated for 48 hrs by [3H]-thymidine incorporation assay
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[PMID: 33289552] |
Deoxylimonin (0-90 μg/mL, 48 h) treatment shows anti-proliferation activities to breast cancer cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MDA-MB-435 and MCF-7 cells
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Concentration:0-90 μg/mL
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Incubation Time:48 hours
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Result:Showed IC50 values of 0.78 μg/mL and 2.50 μg/mL for MDA-MB-435 and MCF-7 cells, respectively.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice injected with acetic acid[1]
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Dosage:70 mg/kg
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Administration:Oral administration; 70 mg/kg; once
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Result:Showed the antinociception efficacy (writhing inhibition rate: 24.61%).
Chemical Information
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CAS No. 989-23-1
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Appearance Solid
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Masse moléculaire 454.51
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Formule C26H30O7
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Color White to off-white
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SMILES
C[C@]1(C2=CC3=O)[C@@](CC[C@]2([C@@](C4=COC=C4)([H])O3)C)([H])[C@]([C@@](C5)([H])OC(C)6C)(COC5=O)[C@@]6([H])CC1=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 100 mg/mL (220.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (284 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2002 mL | 11.0009 mL | 22.0017 mL | 55.0043 mL |
| 5 mM | 0.4400 mL | 2.2002 mL | 4.4003 mL | 11.0009 mL | |
| 10 mM | 0.2200 mL | 1.1001 mL | 2.2002 mL | 5.5004 mL | |
| 15 mM | 0.1467 mL | 0.7334 mL | 1.4668 mL | 3.6670 mL | |
| 20 mM | 0.1100 mL | 0.5500 mL | 1.1001 mL | 2.7502 mL | |
| 25 mM | 0.0880 mL | 0.4400 mL | 0.8801 mL | 2.2002 mL | |
| 30 mM | 0.0733 mL | 0.3667 mL | 0.7334 mL | 1.8335 mL | |
| 40 mM | 0.0550 mL | 0.2750 mL | 0.5500 mL | 1.3751 mL | |
| 50 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1001 mL | |
| 60 mM | 0.0367 mL | 0.1833 mL | 0.3667 mL | 0.9167 mL | |
| 80 mM | 0.0275 mL | 0.1375 mL | 0.2750 mL | 0.6876 mL | |
| 100 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5500 mL |
Deoxylimonin Related Classifications
HY-N7640 Related Classifications
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