DS 4574
DS 4574 is an orally active peptidoleukotriene receptor antagonist and mast cell stabilizer. DS 4574 has antiulcer, gastroprotective and antisecretory effects. DS 4574 inhibits various types of experimental asthma models. DS 4574 protects rats from endotoxin-induced intestinal injury.
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- CAS No.: 118314-35-5
- Formule: C13H16N6OS
- Masse moléculaire:304.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 118314-35-5
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Masse moléculaire 304.37
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Formule C13H16N6OS
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SMILES
O=C1C2=C(N=C3SC(CCC4CCCCC4)=NN13)N=NN2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Tabuchi Y, et al. Protective effect of DS-4574, a peptidoleukotriene receptor antagonist, against endotoxin-induced intestinal injury in rats. Eur J Pharmacol. 1995 Feb 6;273(3):281-4. [Content Brief]
[2]. Yamashika Y, et al. Antisecretory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene antagonism, on gastric acid secretion in the pig. Agents Actions. 1994 Mar;41(1-2):17-20. [Content Brief]
[3]. Tabuchi Y, et al. Effect of DS-4574, a novel peptidoleukotriene antagonist with mast cell stabilizing action, on acute gastric lesions and gastric secretion in rats. Jpn J Pharmacol. 1992 Dec;60(4):335-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)