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GEN-1044

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Based on 1 Customer Validation

GEN-1044 is a bispecific CD3 and oncofetal antigen 5T4 antibody. GEN-1044 shows immunomodulating and antineoplastic activities.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté : 98.83%
  • Masse moléculaire:145.23 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for GEN-1044
  • Experimental Validation Results for GEN-1044
  • Experimental Validation Results for GEN-1044
  • GEN-1044 Chemical Structure
    GEN-1044 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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GEN-1044 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3 (red) with GEN-1044 (HY-P991089). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 NIH-3T3 cells labeling TPBG with GEN-1044 (HY-P991089, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized Human TPBG/5T4, His Tag can bind GEN-1044. The EC50 for this effect is 19.27 ng/mL.

  • GEN-1044 Chemical Structure
    1/16
  • GEN-1044
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3 (red) with GEN-1044 (HY-P991089). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 NIH-3T3 cells labeling TPBG with GEN-1044 (HY-P991089, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized Human TPBG/5T4, His Tag can bind GEN-1044. The EC50 for this effect is 19.27 ng/mL.