FAM76B - family with sequence similarity 76 member B Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143684

About FAM76B

This gene has 13 transcripts (splice variants), 207 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 14.3), lymph node (RPKM 9.9) and 24 other tissues.

Summary

Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

FAM76B Products (2)

mRNA Protein Name
NM_001330357.2 NP_001317286.1 protein FAM76B isoform 2
NM_144664.5 NP_653265.3 protein FAM76B isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence Références Source
located in nuclear speck IDA
IDA: Inferred from direct assay
19266028 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein FAM76B

FAM76B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
FAM76B Q5HYJ3 KRTAP10-8 Homo sapiens P60410
Validated Y2H
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-5 Homo sapiens P60370
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-5 Homo sapiens P60370
Validated Y2H
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-11 Homo sapiens P60412
Y2H Array
25416956
Intra
FAM76B Q5HYJ3 KRTAP10-11 Homo sapiens P60412
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 KRTAP4-7 Homo sapiens Q9BYR0
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 KRTAP4-7 Homo sapiens Q9BYR0
Validated Y2H
25416956
Intra
FAM76B Q5HYJ3 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Array
25416956
Intra
FAM76B Q5HYJ3 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Prey Pooling
25416956
Intra
FAM76B Q5HYJ3 ADO Homo sapiens Q96SZ5
Anti Tag CoIP
28514442
Intra
FAM76B Q5HYJ3 ADO Homo sapiens Q96SZ5
Anti Tag CoIP
33961781
Intra
FAM76B Q5HYJ3 KRTAP5-9 Homo sapiens P26371
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 17

  • Diabetes Mellitus, Insulin-Dependent, 17

  • Iddm17

  • Insulin-Dependent Diabetes Mellitus 17

  • TID17

  • Insulin-Dependent Diabetes Mellitus-17
Mosaic Variegated Aneuploidy Syndrome

  • Warburton-Anyane-Yeboa Syndrome

  • Mva Syndrome

  • Mosaic Variegated Aneuplody Microcephaly Syndrome

  • Warburton Anyane Yeboa Syndrome
Carboxypeptidase N Deficiency

  • Anaphylotoxin Inactivator Deficiency

  • Deficiency Of Carboxypeptidase B

  • CPND
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS04719 FAM76B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FAM76B VGNC VGNC:62124
Bos taurus FAM76B VGNC VGNC:28828
Macaca mulatta FAM76B VGNC VGNC:72389
Rattus norvegicus FAM76B RGD RGD:1311077
Mus musculus FAM76B MGD MGI:1920076
Canis familiaris FAM76B VGNC VGNC:40694
Others FAM76B NCBI