2. Gene
  3. ADO - 2-aminoethanethiol dioxygenase Gene

ADO - 2-aminoethanethiol dioxygenase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C10orf22

Gene ID: 84890 | Gene type: protein coding

About ADO

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:62,804,720-62,808,479 (from NCBI)

This gene has 1 transcript (splice variant) and 247 orthologues.

Summary

Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008]

ADO Products(1)

mRNA Protein Name
NM_032804.6 NP_116193.2 2-aminoethanethiol dioxygenase

ADO Protein Structure

PCO_ADO

PCO_ADO: PCO_ADO (57 - 268)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

2-aminoethanethiol dioxygenase

2-aminoethanethiol (cysteamine) dioxygenase

Related Diseases

Diseases Alias
Ataxia, Sensory, 1, Autosomal Dominant

Autosomal Dominant Sensory Ataxia 1

SNAX1

Adsa

Ataxia, Sensory, Type 1, Autosomal Dominant

Ataxia, Sensory, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9921 Trastuzumab emtansine Inhibitor 99.74% Unkown
HY-P9921A Trastuzumab emtansine (solution) 99.01% Unkown
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148327 AK-IN-1 Inhibitor 99.95% Unkown
HY-103400 8-Chloroadenosine 99.97% Unkown
HY-125927 8-Aminoadenosine 99.94% Unkown
HY-134313 8-NH2-ATP / Unkown
HY-134313A 8-NH2-ATP tetrasodium ≥98.0% Unkown
HY-RS00390 ADO Human Pre-designed siRNA Set A / Unkown
HY-15903 ADOS / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ADO VGNC VGNC:69675
Rattus norvegicus ADO RGD RGD:1308233
Canis familiaris ADO VGNC VGNC:37664
Bos taurus ADO VGNC VGNC:25685
Mus musculus ADO MGD MGI:2685083
Felis catus ADO VGNC VGNC:59647
Others ADO NCBI