PI16 - peptidase inhibitor 16 Gene

Also Known as CD364; PSPBP; CRISP9; MSMBBP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221476

About PI16

This gene has 4 transcripts (splice variants) and 85 orthologues. Biased expression in urinary bladder (RPKM 35.7), heart (RPKM 28.3) and 12 other tissues.

Summary

Predicted to enable peptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to act upstream of or within negative regulation of cell growth involved in cardiac muscle cell development. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

PI16 Products (2)

mRNA Protein Name
NM_001199159.2 NP_001186088.1 peptidase inhibitor 16 precursor
NM_153370.3 NP_699201.2 peptidase inhibitor 16 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PI16 Protein Structure

CAP

CAP: Cysteine-rich secretory protein family (38 - 165)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 463 a.a.
Protein Preferred Names Protein Names

peptidase inhibitor 16

  • PSP94-binding protein

PI16 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
PI16 Q6UXB8 TMEM86A Homo sapiens Q8N2M4
Validated Y2H
32296183
Intra
PI16 Q6UXB8 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

PI16 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P84644 CD364 Antibody (YA4341) WB, IHC-P, FC, ELISA Human
HY-P84644A CD364 Antibody (YA4341)(PBS only) WB, IHC-P, FC, ELISA Human

Related Diseases

Diseases Alias
Corneal Dystrophy, Meesmann, 1

  • Meesmann Corneal Dystrophy

  • Mecd

  • Corneal Dystrophy, Meesmann Epithelial

  • Juvenile Hereditary Epithelial Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial Of Meesmann

  • MECD1

  • Meesmann Corneal Dystrophy 1

  • Meesmann Corneal Epithelial Dystrophy

  • Meesmann Epithelial Corneal Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial, Of Meesmann

  • Stocker-Holt Dystrophy

  • Meesman Dystrophy

  • Meesman'S Corneal Dystrophy

  • Juvenile Hereditary Epithelial Dystrophy Of Meesmann

  • Corneal Dystrophy, Meesmann 1

  • Juvenile Epithelial Corneal Dystrophy Of Meesmann

  • Mcd

  • Dystrophy, Corneal, Meesmann
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type

  • Methylcobalamin Deficiency, Cblg Type

  • HMAG

  • Methionine Synthase Deficiency

  • Methylcobalamin Deficiency Type Cblg

  • Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism, Cblg Complementation Type

  • Homocystinuria-Megaloblastic Anemia Cblg Type

  • Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism Cblg Complementation Type

  • Methylcobalamin Deficiency Cbl G Type

  • Homocystinuria Due To Defect In Methylation Cbl G

  • Cblg

  • Functional Methionine Synthase Deficiency Type Cblg

  • Methylcobalamin Deficiency Cblg Type

  • Arakawa Syndrome 2
Retinitis Pigmentosa 61

  • RP61

  • Retinitis Pigmentosa, Type 61
Epithelial And Subepithelial Dystrophy
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS10462 PI16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-165648S PtdIns-(1-palmitoyl-d9, 2-palmitoyl) sodium salt / Unkown
HY-RS19366 Pi16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25858 Pi16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PI16 RGD RGD:1304760
Mus musculus PI16 MGD MGI:1921366
Felis catus PI16 VGNC VGNC:97555
Macaca mulatta PI16 VGNC VGNC:81497
Canis familiaris PI16 VGNC VGNC:44515
Bos taurus PI16 VGNC VGNC:32853
Others PI16 NCBI