Fmnl3 - formin-like 3 Gene

Also Known as Wbp3; FBP11; mKIAA2014; 2700073B04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22379

Summary

Enables GTPase activating protein binding activity. Predicted to be involved in cell migration; cortical actin Cytoskeleton organization; and regulation of cell shape. Predicted to act upstream of or within angiogenesis. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and retina. Orthologous to human FMNL3 (formin like 3). [provided by Alliance of Genome Resources, Apr 2022]

Fmnl3 Products (3)

mRNA Protein Name
NM_001310622.1 NP_001297551.1 formin-like protein 3 isoform 2
NM_001310623.1 NP_001297552.1 formin-like protein 3 isoform 3
NM_011711.2 NP_035841.1 formin-like protein 3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables GTPase activating protein binding IDA
IDA: Inferred from direct assay
21148482 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9171351 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formin-like protein 3

  • WW domain binding protein 3

  • formin-like 3 protein

Fmnl3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Cross
Fmnl3 Q6ZPF4 SRGAP2 Homo sapiens O75044
Y2H
21148482
Cross
Fmnl3 Q6ZPF4 SRGAP2 Homo sapiens O75044
Peptide Array
21148482
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05004 FMNL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20410 Fmnl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26919 Fmnl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fmnl3 NCBI NCBI:91010