country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

GPR141 - G protein-coupled receptor 141 Gene

Also Known as PGR13

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 353345

About GPR141

Cytogenetic location: 7p14.1 Genomic coordinates (GRCh38): 7:37,683,766-37,743,835 (from NCBI)

This gene has 5 transcripts (splice variants), 195 orthologues and 7 paralogues. Biased expression in bone marrow (RPKM 2.2), appendix (RPKM 0.5) and 10 other tissues.

Summary

GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]

GPR141 Products (4)

mRNA	Protein	Name
NM_001329993.2	NP_001316922.1	probable G-protein coupled receptor 141
NM_001329994.2	NP_001316923.1	probable G-protein coupled receptor 141
NM_001381946.1	NP_001368875.1	probable G-protein coupled receptor 141
NM_181791.3	NP_861456.1	probable G-protein coupled receptor 141

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Références	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR141 Protein Structure

7tm_1

0
100
200
305 a.a.

Protein Preferred Names	Protein Names
probable G-protein coupled receptor 141	G-protein coupled receptor PGR13

GPR141 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Références
Intra	GPR141	Q7Z602	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	GPR141	Q7Z602	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	GPR141	Q7Z602	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
Intra	GPR141	Q7Z602	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
Intra	GPR141	Q7Z602	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	CTSD	Homo sapiens	P07339	Y2H Array	32814053
Intra	GPR141	Q7Z602	CTSD	Homo sapiens	P07339	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	CTSD	Homo sapiens	P07339	Validated Y2H	32814053
Intra	GPR141	Q7Z602	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	GPR141	Q7Z602	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	GPR141	Q7Z602	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
Intra	GPR141	Q7Z602	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
Intra	GPR141	Q7Z602	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	GPR141	Q7Z602	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	GPR141	Q7Z602	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	GPR141	Q7Z602	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	GPR141	Q7Z602	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	TTR	Homo sapiens	P02766	Validated Y2H	32814053
Intra	GPR141	Q7Z602	TTR	Homo sapiens	P02766	Y2H Array	32814053
Intra	GPR141	Q7Z602	TTR	Homo sapiens	P02766	Y2H Pooling	32814053
Intra	GPR141	Q7Z602	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	GPR141	Q7Z602	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	GPR141	Q7Z602	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Diamond-Blackfan Anemia 4	DBA4 Rps17-Related Diamond-Blackfan Anemia Anemia, Diamond-Blackfan, Type 4
Townes-Brocks Syndrome	Townes Syndrome Renal-Ear-Anal-Radial Syndrome Anus, Imperforate, With Hand, Foot And Ear Anomalies Imperforate Anus-Hand, Foot And Ear Anomalies Syndrome Rear Syndrome Sensorineural Deafness With Imperforate Anus And Hypoplastic Thumbs Tbs Deafness, Sensorineural, With Imperforate Anus And Hypoplastic Thumbs Imperforate Anus With Hand, Foot And Ear Anomalies Anal-Ear-Renal-Radial Malformation Syndrome Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome Imperforate Anus-Hand And Foot Anomalies Syndrome Sensorineural Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome Sensorineural Hearing Loss With Imperforate Anus And Hypoplastic Thumbs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-RS05663	GPR141 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21860	Gpr141 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28377	Gpr141 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	GPR141	VGNC	VGNC:62675
Mus musculus	GPR141	MGD	MGI:2672983
Macaca mulatta	GPR141	VGNC	VGNC:81323
Canis familiaris	GPR141	VGNC	VGNC:41401
Bos taurus	GPR141	VGNC	VGNC:52783
Rattus norvegicus	GPR141	RGD	RGD:727906
Others	GPR141	NCBI