DNAI7 - dynein axonemal intermediate chain 7 Gene

Also Known as LAS1; CASC1; CFAP94; PPP1R54

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55259

Summary

Predicted to enable beta-tubulin binding activity and microtubule binding activity. Predicted to be located in cilium and microtubule Cytoskeleton. Predicted to be part of axonemal dynein complex. Predicted to be active in axoneme and cytoplasmic microtubule. [provided by Alliance of Genome Resources, Jul 2025]
Biased expression in lymph node (RPKM 12.5), testis (RPKM 9.5) and 11 other tissues.

DNAI7 Products (15)

mRNA Protein Name
NM_001082972.3 NP_001076441.1 dynein axonemal intermediate chain 7 isoform c
NM_001082973.3 NP_001076442.2 dynein axonemal intermediate chain 7 isoform b
NM_001204101.3 NP_001191030.2 dynein axonemal intermediate chain 7 isoform e
NM_001204102.3 NP_001191031.2 dynein axonemal intermediate chain 7 isoform d
NM_001319977.2 NP_001306906.1 dynein axonemal intermediate chain 7 isoform f
NM_001319978.2 NP_001306907.2 dynein axonemal intermediate chain 7 isoform d
NM_001352061.2 NP_001338990.2 dynein axonemal intermediate chain 7 isoform d
NM_001352062.2 NP_001338991.1 dynein axonemal intermediate chain 7 isoform g
NM_001352063.2 NP_001338992.2 dynein axonemal intermediate chain 7 isoform h
NM_001352064.2 NP_001338993.2 dynein axonemal intermediate chain 7 isoform i
NM_001352065.2 NP_001338994.2 dynein axonemal intermediate chain 7 isoform j
NM_001352066.2 NP_001338995.2 dynein axonemal intermediate chain 7 isoform k
NM_001352067.2 NP_001338996.2 dynein axonemal intermediate chain 7 isoform l
NM_001352068.2 NP_001338997.1 dynein axonemal intermediate chain 7 isoform m
NM_018272.5 NP_060742.4 dynein axonemal intermediate chain 7 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNAI7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
DNAI7 Q6TDU7 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Intra
DNAI7 Q6TDU7 NME7 Homo sapiens Q9Y5B8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS03852 DNAH7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03855 DNAI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03856 DNAI2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown